What is the active role of Pazeo in treating allergic conjunctivitis?

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Pazeo, which contains the active ingredient olopatadine, plays an important role in treating allergic conjunctivitis by stabilizing mast cells. Mast cells are a type of immune cell that, when activated by allergens, release histamine and other mediators that contribute to allergic symptoms such as itching, redness, and swelling of the eyes. By stabilizing these mast cells, Pazeo helps to prevent them from releasing histamine, thereby alleviating allergy symptoms before they can occur.

Stabilization of mast cells is crucial because it not only reduces the immediate symptoms associated with the release of histamine but also modulates the overall inflammatory response. This mechanism can lead to prolonged relief from symptoms and effectively manage allergic reactions as they occur.

In contrast, acting as a host antibody is not a function of Pazeo, as it is not designed to mimic or enhance the body’s immune antibodies. Increasing tear production is also not a function of Pazeo; its primary action is not related to tear dynamics. Lastly, though blocking histamine release is a beneficial result of mast cell stabilization, it is more accurate to say that Pazeo prevents the release by stabilizing the mast cells rather than actively blocking histamine release itself. This distinction underscores the mechanism

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